Buy Motilium – Domperidone online 10MG.
Motilium – antiemetic drug, which is able to stimulate the motility of the gastrointestinal tract.
The drug for children and adults alleviates the condition with nausea, heartburn, vomiting, belching, bloating, heaviness in the stomach and excessive gas generation. When poisoning and the above conditions, Motilium restores disturbed processes and accelerates recovery.
Produced in the form of tablets, coated with a shell and suspension for oral administration. Before using the drug to treat children should consult a pediatrician, there are contraindications.
The active substance Motilium quickly absorbed and reaches the maximum presence in the blood plasma within an hour after taking the medication. Reduced acidity of the stomach worsens the absorption of the drug.
Domperidone does not accumulate in the body, is completely metabolized in the digestive tract and liver and is excreted with waste of vital activity. At oral intake with urine, up to 31% of domperidone is excreted, with feces – up to 66%. A small fraction of the substance is excreted from the body in its original form. Half-life in a healthy person is about 8 hours.
The study of distribution of the drug on experimental animals indicates a low penetration of domperidone into the brain. Data on the pharmacokinetics of the drug were obtained in the study of adult volunteers.
Indications for use
What helps? Motilium is used in diseases of the upper parts of the digestive tract, which reduce motor-evacuation functions.
Indications for use:
☛ abdominal pain;
☛ feeling of overfilling in epigastrium;
☛ heartburn, flatulence;
☛ frequent regurgitation, cyclic vomiting;
☛ nausea and vomiting caused by a violation of diet or drug therapy;
☛ disruption of the stomach in children;
☛ a complex of dyspeptic symptoms that are associated with a slowdown in gastric emptying.
Suspension is used for gastrointestinal reflux and regurgitation in newborns.
Use in pregnancy and lactation
Data on the use of Motilium during pregnancy is not enough.
To date, there is no evidence of an increased risk of human developmental malformations. Nevertheless, Motilium should be prescribed during pregnancy only in cases where the expected benefit of therapy for the mother exceeds the potential risk to the fetus.
In women, the concentration of domperidone in breast milk is 10-50% of the corresponding plasma concentration and does not exceed 10 ng / ml. The total amount of domperidone excreted into breast milk is less than 7 μg / day when the maximum permissible doses are applied. It is not known whether this level has a negative effect on newborns. Therefore, if you need to use the drug Motilium during lactation, breastfeeding should be discontinued.